🐷 Organ Scarcity Solution: Scientific and Ethical Hurdles in the Xenotransplantation Market
The Xenotransplantation Market involves the transplantation of living cells, tissues, or organs from one species to another, specifically non-human animals (most commonly genetically modified pigs) into humans. The market is driven by the acute, persistent global shortage of human organs for transplantation.Xenotransplantation Market.
The market’s progress hinges on overcoming two major challenges: Immunological Rejection and Safety Concerns (e.g., the potential transmission of porcine endogenous retroviruses, or $\text{PERVs}$). Scientific breakthroughs in Genetic Engineering, particularly using $\text{CRISPR/Cas9}$ technology to "humanize" pig organs (removing genes that trigger hyperacute rejection and inserting human genes to promote immune acceptance), have brought clinical xenotransplantation closer to reality. Navigating the complex Ethical and Regulatory Hurdles associated with animal welfare, public safety, and informed consent is equally critical for the continued development
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