When Bacteria Attach: Understanding the Complex Science of Microbial Communities on Artificial Surfaces and its Role in Chronic Infection
The primary reason for the persistence and recurrence of orthopedic implant infections lies in a biological phenomenon known as biofilm formation. When bacteria encounter the non-biological surface of an implant, they adhere and rapidly embed themselves in a self-produced matrix composed of polysaccharides, proteins, and DNA. This sticky, protective layer acts as a fortress, effectively...
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